Molecule Details
InChIKeyJUUFLLKHNYWHKP-UHFFFAOYSA-N
Compound Name3-(2-Methyl-1,3-benzoxazol-5-yl)-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-4-amine
Canonical SMILESCc1nc2cc(-c3nn(C(C)C)c4ncnc(N)c34)ccc2o1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)12
Pfam Stratification Cross-Family
Avg pChEMBL6.81
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (12)
Target Gene Organism Category Pfam pChEMBL Type Source
Q6P5Z2 PKN3 Homo sapiens Human PF02185 PF00069 PF00433 7.9 Kd ChEMBL
Q96S53 TESK2 Homo sapiens Human PF07714 7.8 Kd ChEMBL
Q04771 ACVR1 Homo sapiens Human PF01064 PF07714 PF08515 7.4 Kd ChEMBL
O00238 BMPR1B Homo sapiens Human PF01064 PF07714 PF08515 6.9 Kd ChEMBL
Q16832 DDR2 Homo sapiens Human PF21114 PF00754 PF07714 6.9 Kd ChEMBL
P48730 CSNK1D Homo sapiens Human PF00069 6.8 Kd ChEMBL
P49674 CSNK1E Homo sapiens Human PF00069 6.8 Kd ChEMBL
O43353 RIPK2 Homo sapiens Human PF00619 PF07714 6.8 Kd ChEMBL
Q9UBE8 NLK Homo sapiens Human PF00069 6.3 Kd ChEMBL
P36896 ACVR1B Homo sapiens Human PF01064 PF00069 PF08515 6.1 Kd ChEMBL
Q08345 DDR1 Homo sapiens Human PF21114 PF00754 PF07714 6.0 Kd ChEMBL
Q13705 ACVR2B Homo sapiens Human PF01064 PF00069 6.0 Kd ChEMBL