Molecule Details
| InChIKey | JUOSGGQXEBBCJB-GORDUTHDSA-N |
|---|---|
| Compound Name | Rivanicline |
| Canonical SMILES | CNCC/C=C/c1cccnc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.59 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB05855 |
|---|---|
| Drug Name | Rivanicline |
| CAS Number | 15585-43-0 |
| Groups | experimental |
| ATC Codes | nan |
| Description | Rivanicline (TC-2403, RJR-2403, (E)-metanicotine) is a partial agonist at neuronal nicotinic acetylcholine receptors, binding primarily to the α4β2 subtype. It was originally developed as a potential treatment for Alzheimer's disease for its nootropic effects but has also been found to inhibit the p... |
Categories: Alkaloids Pyridines Solanaceous Alkaloids
Cross-references: BindingDB: 50061561 CHEMBL132966 ChemSpider: 4470511 PubChem:5310967 PubChem:175427044 Wikipedia: Rivanicline ZINC: ZINC000001543478