Molecule Details
InChIKeyJTYYECWUMLHCSJ-UHFFFAOYSA-N
Compound NameN-[5-(3-benzylbenzimidazol-5-yl)-1H-pyrazol-3-yl]-4-[(1-methylpiperidin-4-yl)amino]benzamide
Canonical SMILESCN1CCC(Nc2ccc(C(=O)Nc3cc(-c4ccc5ncn(Cc6ccccc6)c5c4)[nH]n3)cc2)CC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)8
Pfam Stratification Homologous
Avg pChEMBL6.77
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (8)
Target Gene Organism Category Pfam pChEMBL Type Source
P36888 FLT3 Homo sapiens Human PF00047 PF07714 7.9 IC50 ChEMBL;BindingDB
Q16288 NTRK3 Homo sapiens Human PF07679 PF00047 PF13855 PF16920 PF01462 PF07714 7.4 IC50 ChEMBL;BindingDB
P07333 CSF1R Homo sapiens Human PF00047 PF25305 PF07714 6.8 IC50 ChEMBL;BindingDB
P11362 FGFR1 Homo sapiens Human PF07679 PF00047 PF07714 6.7 IC50 ChEMBL;BindingDB
P16234 PDGFRA Homo sapiens Human PF07679 PF25305 PF07714 6.4 IC50 ChEMBL;BindingDB
P10721 KIT Homo sapiens Human PF00047 PF07714 6.4 IC50 ChEMBL;BindingDB
Q16620 NTRK2 Homo sapiens Human PF07679 PF13855 PF16920 PF01462 PF07714 6.3 IC50 ChEMBL;BindingDB
P09619 PDGFRB Homo sapiens Human PF00047 PF13927 PF25305 PF07714 6.2 IC50 ChEMBL;BindingDB