Molecule Details
InChIKeyJTVBXQAYBIJXRP-SNVBAGLBSA-N
Compound NameY-33075
Canonical SMILESC[C@@H](N)c1ccc(C(=O)Nc2ccnc3[nH]ccc23)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)20
Pfam Stratification Cross-Family
Avg pChEMBL6.9
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (20)
Target Gene Organism Category Pfam pChEMBL Type Source
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 8.4 IC50 ChEMBL;BindingDB
P49759 CLK1 Homo sapiens Human PF00069 7.8 Kd ChEMBL
Q16513 PKN2 Homo sapiens Human PF02185 PF00069 PF00433 7.5 Kd ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 7.5 IC50 ChEMBL;BindingDB
Q05655 PRKCD Homo sapiens Human PF00130 PF21494 PF00069 PF00433 7.5 Kd ChEMBL
Q9Y5S2 CDC42BPB Homo sapiens Human PF00130 PF00780 PF08826 PF15796 PF25346 PF00069 7.5 Kd ChEMBL
O14578 CIT Homo sapiens Human PF00780 PF00169 PF00069 PF00433 7.2 IC50 ChEMBL
Q9Y2K2 SIK3 Homo sapiens Human PF00069 PF23312 7.2 Kd ChEMBL
Q04759 PRKCQ Homo sapiens Human PF00130 PF21494 PF00069 PF00433 7.0 Kd ChEMBL
Q6ZSR9 Homo sapiens Human PF15282 7.0 Kd ChEMBL
Q2M2I8 AAK1 Homo sapiens Human PF00069 6.9 Kd ChEMBL
Q9NSY1 BMP2K Homo sapiens Human PF15282 PF00069 6.8 Kd ChEMBL
Q16512 PKN1 Homo sapiens Human PF02185 PF00069 PF00433 6.6 Kd ChEMBL
P36894 BMPR1A Homo sapiens Human PF01064 PF07714 PF08515 6.5 Kd ChEMBL
Q9BZL6 PRKD2 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.2 Kd ChEMBL
O94806 PRKD3 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.1 Kd ChEMBL
P48729 CSNK1A1 Homo sapiens Human PF00069 6.1 Kd ChEMBL
Q9Y6M4 CSNK1G3 Homo sapiens Human PF12605 PF00069 6.1 Kd ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 6.0 Kd ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 6.0 Kd ChEMBL