JTLQSWMRBFBYEA-IUODEOHRSA-N

InChIKey	`JTLQSWMRBFBYEA-IUODEOHRSA-N`
Canonical SMILES	`O=C1NC[C@@H](O)COc2ncc(F)cc2[C@H]2CCCN2c2ccn3ncc1c3n2`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	7.89
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P08922	ROS1	Homo sapiens	Human	PF00041 PF07714	8.5	IC50	ChEMBL;BindingDB
P04629	NTRK1	Homo sapiens	Human	PF13855 PF16920 PF07714 PF18613	7.3	IC50	ChEMBL;BindingDB