Molecule Details
InChIKeyJTKFRFMSUBOCIQ-UHFFFAOYSA-N
Compound Name2-(2H-indazol-3-yl)-1H-1,3-benzodiazole
Canonical SMILESc1ccc2[nH]c(-c3n[nH]c4ccccc34)nc2c1
Clinical Status Clinical Multi-Target
Targets (Human+Pathogen)4
Pfam Stratification Cross-Family
Avg pChEMBL6.12
SourceBindingDB;ChEMBL;TTD_MultiTarget
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB07959
Drug Name3-(1H-BENZIMIDAZOL-2-YL)-1H-INDAZOLE
CAS Numbernan
Groups experimental
ATC Codes nan
Descriptionnan

Cross-references: BindingDB: 16590 CHEMBL383990 ChemSpider: 10806321 PDB: IDZ PubChem:5327123 PubChem:99444430 ZINC: ZINC000014961821
Target Activities (4)
Target Gene Organism Category Pfam pChEMBL Type Source
P11362 FGFR1 Homo sapiens Human PF07679 PF00047 PF07714 6.1 pIC50 TTD_MultiTarget
P17948 FLT1 Homo sapiens Human PF07679 PF00047 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 6.1 IC50 ChEMBL;BindingDB
P49841 GSK3B Homo sapiens Human PF00069 6.1 IC50 BindingDB
P06493 CDK1 Homo sapiens Human PF00069 6.1 IC50 BindingDB
DrugBank Target Actions (5)
Target Gene Target Name Action Type
O14757 CHEK1 Serine/threonine-protein kinase Chk1 binder targets
P09619 PDGFRB Platelet-derived growth factor receptor beta inhibitor targets
P11362 FGFR1 Fibroblast growth factor receptor 1 inhibitor targets
P17948 FLT1 Vascular endothelial growth factor receptor 1 inhibitor targets
P35968 KDR Vascular endothelial growth factor receptor 2 inhibitor targets