3-{4-[2-(4-tert-Butyl-phenyl)-2-(quinolin-3-ylcarbamoyl)-ethyl]-benzoylamino}-propionic acid

InChIKey	`JTIOTPJAIFIFFX-UHFFFAOYSA-N`
Compound Name	3-{4-[2-(4-tert-Butyl-phenyl)-2-(quinolin-3-ylcarbamoyl)-ethyl]-benzoylamino}-propionic acid
Canonical SMILES	`CC(C)(C)c1ccc(C(Cc2ccc(C(=O)NCCC(=O)O)cc2)C(=O)Nc2cnc3ccccc3c2)cc1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	10
Pfam Stratification	Cross-Family
Avg pChEMBL	6.38
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P47871	GCGR	Homo sapiens	Human	PF00002 PF02793	8.0	Ki	ChEMBL;BindingDB
O43306	ADCY6	Homo sapiens	Human	PF16214 PF06327 PF00211	6.2	Ki	ChEMBL
O60266	ADCY3	Homo sapiens	Human	PF16214 PF00211	6.2	Ki	ChEMBL
O60503	ADCY9	Homo sapiens	Human	PF00211	6.2	Ki	ChEMBL;BindingDB
O95622	ADCY5	Homo sapiens	Human	PF16214 PF06327 PF00211	6.2	Ki	ChEMBL
P40145	ADCY8	Homo sapiens	Human	PF16214 PF06327 PF00211	6.2	Ki	ChEMBL
P51828	ADCY7	Homo sapiens	Human	PF16214 PF06327 PF00211	6.2	Ki	ChEMBL
Q08462	ADCY2	Homo sapiens	Human	PF16214 PF06327 PF00211	6.2	Ki	ChEMBL
Q08828	ADCY1	Homo sapiens	Human	PF16214 PF00211	6.2	Ki	ChEMBL
Q8NFM4	ADCY4	Homo sapiens	Human	PF16214 PF06327 PF00211	6.2	Ki	ChEMBL