Molecule Details
InChIKeyJSNFRYBHBVDHSG-NEPJUHHUSA-N
Canonical SMILESNc1nc(O)c2c(n1)NC[C@@H]1CN(c3ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc3)C(=O)N21
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL6.6
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P11586 MTHFD1 Homo sapiens Human PF01268 PF00763 PF02882 7.0 IC50 ChEMBL;BindingDB
P13995 MTHFD2 Homo sapiens Human PF00763 PF02882 6.2 IC50 ChEMBL;BindingDB