Molecule Details
| InChIKey | JSASWRWALCMOQP-UHFFFAOYSA-N |
|---|---|
| Canonical SMILES | CC(C)N(CCC(=O)c1ccc2ccccc2c1)Cc1ccccc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.67 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB17064 |
|---|---|
| Drug Name | ZM-39923 |
| CAS Number | 273727-89-2 |
| Groups | experimental |
| ATC Codes | nan |
| Description | ZM-39923 is a small molecule that inhibits Janus kinase and human tissue transglutaminase (TGM2).[A253177] |
Cross-references: BindingDB: 81346 ChEBI: 92715 CHEMBL596674 ChemSpider: 3665 ZINC: ZINC000001487934
Target Activities (2)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P52333 | JAK3 | Homo sapiens | Human | PF18379 PF18377 PF17887 PF07714 PF21990 | 7.1 | IC50 | ChEMBL;BindingDB |
| P0DTD1 | rep | Severe acute respiratory syndrome coronavirus 2 | Pathogen | PF13087 PF16251 PF11501 PF12379 PF12124 PF11633 PF06471 PF06460 PF09401 PF20631 PF20633 PF20632 PF19215 PF19216 PF19219 PF19211 PF19218 PF16348 PF19217 PF19213 PF08716 PF08717 PF08710 PF08715 PF06478 PF01661 PF05409 PF00680 | 6.2 | IC50 | ChEMBL |