N-(2,6-diethylphenyl)-8-[2-methoxy-4-(4-methyl-1,4-diazepane-1-carbonyl)anilino]-1-methyl-4,5-dihydropyrazolo[4,5-h]quinazoline-3-carboxamide

InChIKey	`JRZGFHZNTXYGPL-UHFFFAOYSA-N`
Compound Name	N-(2,6-diethylphenyl)-8-[2-methoxy-4-(4-methyl-1,4-diazepane-1-carbonyl)anilino]-1-methyl-4,5-dihydropyrazolo[4,5-h]quinazoline-3-carboxamide
Canonical SMILES	`CCc1cccc(CC)c1NC(=O)c1nn(C)c2c1CCc1cnc(Nc3ccc(C(=O)N4CCCN(C)CC4)cc3OC)nc1-2`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	6.85
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P33981	TTK	Homo sapiens	Human	PF00069	7.7	IC50	ChEMBL;BindingDB
O14965	AURKA	Homo sapiens	Human	PF00069	6.4	IC50	ChEMBL;BindingDB
P24941	CDK2	Homo sapiens	Human	PF00069	6.4	pIC50	TTD_MultiTarget