Molecule Details
InChIKeyJRNXAQINDCOHGS-CBINBANVSA-N
Compound Name[4-amino-2-[[(2S)-2-bicyclo[2.2.1]heptanyl]amino]-1,3-thiazol-5-yl]-(2-nitrophenyl)methanone
Canonical SMILESNc1nc(N[C@H]2CC3CCC2C3)sc1C(=O)c1ccccc1[N+](=O)[O-]
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)13
Pfam Stratification Cross-Family
Avg pChEMBL7.08
SourceBindingDB;ChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (13)
Target Gene Organism Category Pfam pChEMBL Type Source
O60563 CCNT1 Homo sapiens Human PF00134 PF21797 8.3 IC50 ChEMBL
O60583 CCNT2 Homo sapiens Human PF00134 PF21797 8.3 IC50 ChEMBL
P50750 CDK9 Homo sapiens Human PF00069 8.3 IC50 ChEMBL
O95067 CCNB2 Homo sapiens Human PF02984 PF00134 6.9 IC50 ChEMBL
P06493 CDK1 Homo sapiens Human PF00069 6.9 IC50 ChEMBL
P14635 CCNB1 Homo sapiens Human PF02984 PF00134 6.9 IC50 ChEMBL
Q8WWL7 CCNB3 Homo sapiens Human PF02984 PF00134 6.9 IC50 ChEMBL
Q00535 CDK5 Homo sapiens Human PF00069 6.8 IC50 ChEMBL
Q15078 CDK5R1 Homo sapiens Human PF03261 6.8 IC50 ChEMBL
P20248 CCNA2 Homo sapiens Human PF02984 PF00134 PF16500 6.6 IC50 ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.6 IC50 ChEMBL
P78396 CCNA1 Homo sapiens Human PF02984 PF00134 PF16500 6.6 IC50 ChEMBL
P50613 CDK7 Homo sapiens Human PF00069 6.3 IC50 ChEMBL