Molecule Details
InChIKeyJRNGHBUUFQDBPT-LAQRGFTBSA-N
Compound Nameinhibitor 1 [Colombo et al., 2012]
Canonical SMILESC[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)c1nc2ccccc2s1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)8
Pfam Stratification Homologous
Avg pChEMBL9.02
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (8)
Target Gene Organism Category Pfam pChEMBL Type Source
Q8IU80 TMPRSS6 Homo sapiens Human PF00057 PF01390 PF00089 11.0 Ki ChEMBL;BindingDB
Q9Y5Y6 ST14 Homo sapiens Human PF00431 PF00057 PF01390 PF00089 11.0 Ki ChEMBL
P07477 PRSS1 Homo sapiens Human PF00089 9.0 Ki ChEMBL
P07478 PRSS2 Homo sapiens Human PF00089 9.0 Ki ChEMBL
P35030 PRSS3 Homo sapiens Human PF00089 9.0 Ki ChEMBL
P05981 HPN Homo sapiens Human PF09272 PF00089 9.0 Ki ChEMBL
O60235 TMPRSS11D Homo sapiens Human PF01390 PF00089 8.1 Ki ChEMBL
P00734 F2 Homo sapiens Human PF00594 PF00051 PF09396 PF00089 6.2 Ki ChEMBL