Molecule Details
| InChIKey | JREBTSVEMYTHEU-UHFFFAOYSA-N |
|---|---|
| Compound Name | (4-Fluoro-phenyl)-{1-[2-(2-iodo-phenyl)-ethyl]-piperidin-4-yl}-methanone |
| Canonical SMILES | O=C(c1ccc(F)cc1)C1CCN(CCc2ccccc2I)CC1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.86 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P28223 | HTR2A | Homo sapiens | Human | PF00001 | 8.7 | Ki | ChEMBL;BindingDB |
| P34969 | HTR7 | Homo sapiens | Human | PF00001 | 8.4 | Ki | ChEMBL;BindingDB |
| P28335 | HTR2C | Homo sapiens | Human | PF00001 | 7.5 | Ki | ChEMBL;BindingDB |
| P50406 | HTR6 | Homo sapiens | Human | PF00001 | 6.9 | Ki | ChEMBL;BindingDB |