Molecule Details
| InChIKey | JQYYZEGXJPYRRZ-UHFFFAOYSA-N |
|---|---|
| Compound Name | 2-Amino-5,5-bis(4-methoxyphenyl)-3-(oxan-4-yl)imidazol-4-one |
| Canonical SMILES | COc1ccc(C2(c3ccc(OC)cc3)NC(=N)N(C3CCOCC3)C2=O)cc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.48 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P14091 | CTSE | Homo sapiens | Human | PF07966 PF00026 | 6.3 | IC50 | ChEMBL;BindingDB |
| P46925 | PMII | Plasmodium falciparum (isolate HB3) | Pathogen | PF00026 | 8.2 | IC50 | ChEMBL;BindingDB |
| Q17SB2 | Plasmodium falciparum | Pathogen | PF00026 | 7.8 | IC50 | ChEMBL | |
| Q8IM16 | PMIV | Plasmodium falciparum (isolate 3D7) | Pathogen | PF00026 | 7.7 | IC50 | BindingDB |