Molecule Details
InChIKeyJQXUGPKGNONGRJ-UHFFFAOYSA-N
Canonical SMILESCCS(=O)(=O)N1CC(CC#N)(n2cc(-c3nc(Nc4ccc(C(=O)NCCCCOc5ccc(C6CCC(=O)NC6=O)cc5)cc4)nc4[nH]ccc34)cn2)C1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Cross-Family
Avg pChEMBL8.78
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
O60674 JAK2 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 9.8 Kd ChEMBL;BindingDB
Q96SW2 CRBN Homo sapiens Human PF02190 PF03226 7.7 IC50 ChEMBL;BindingDB