8-[3-[[4-methyl-5-(2-methylquinolin-5-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-6,7,9,10-tetrahydro-4H-[1,4]oxazino[2,3-h][3]benzazepin-3-one

InChIKey	`JQEQULOLEPTBRS-UHFFFAOYSA-N`
Compound Name	8-[3-[[4-methyl-5-(2-methylquinolin-5-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-6,7,9,10-tetrahydro-4H-[1,4]oxazino[2,3-h][3]benzazepin-3-one
Canonical SMILES	`Cc1ccc2c(-c3nnc(SCCCN4CCc5cc6c(cc5CC4)OCC(=O)N6)n3C)cccc2n1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	7.2
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q12809	KCNH2	Homo sapiens	Human	PF00027 PF00520 PF13426	8.2	IC50	ChEMBL;BindingDB
P35367	HRH1	Homo sapiens	Human	PF00001	6.8	Ki	ChEMBL;BindingDB
P35462	DRD3	Homo sapiens	Human	PF00001	6.6	Ki	ChEMBL;BindingDB