N-(5-Cyclobutyl-thiazol-2-yl)-2-isoquinolin-5-yl-acetamide

InChIKey	`JPWSUSDWOYHFRI-UHFFFAOYSA-N`
Compound Name	N-(5-Cyclobutyl-thiazol-2-yl)-2-isoquinolin-5-yl-acetamide
Canonical SMILES	`O=C(Cc1cccc2cnccc12)Nc1ncc(C2CCC2)s1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	7.4
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q00535	CDK5	Homo sapiens	Human	PF00069	7.9	IC50	ChEMBL;BindingDB
P24864	CCNE1	Homo sapiens	Human	PF02984 PF00134	7.2	IC50	ChEMBL
P24941	CDK2	Homo sapiens	Human	PF00069	7.2	IC50	ChEMBL;BindingDB