Molecule Details
InChIKeyJPNQTKSRCYBFJQ-UHFFFAOYSA-N
Compound NameUS10544143, Example 525
Canonical SMILESCc1cc2[nH]c(-c3cc(C)c4ncnn4c3)c(C(C)C)c2nc1C1CCNCC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Homologous
Avg pChEMBL7.72
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9NYK1 TLR7 Homo sapiens Human PF13855 PF01582 9.7 IC50 ChEMBL;BindingDB
Q9NR97 TLR8 Homo sapiens Human PF13855 PF01582 7.3 IC50 ChEMBL;BindingDB
Q9NR96 TLR9 Homo sapiens Human PF18837 PF13516 PF13855 PF01582 6.1 IC50 ChEMBL;BindingDB