N,N'-Bis(2-{(Biphenyl-4-Ylsulfonyl)[(2r)-1-(Hydroxyamino)-3-Methyl-1-Oxobutan-2-Yl]amino}ethyl)benzene-1,3-Dicarboxamide (Non-Preferred Name)

InChIKey	`JPMXJRBHCOULJI-NCRNUEESSA-N`
Compound Name	N,N'-Bis(2-{(Biphenyl-4-Ylsulfonyl)[(2r)-1-(Hydroxyamino)-3-Methyl-1-Oxobutan-2-Yl]amino}ethyl)benzene-1,3-Dicarboxamide (Non-Preferred Name)
Canonical SMILES	`CC(C)[C@H](C(=O)NO)N(CCNC(=O)c1cccc(C(=O)NCCN([C@@H](C(=O)NO)C(C)C)S(=O)(=O)c2ccc(-c3ccccc3)cc2)c1)S(=O)(=O)c1ccc(-c2ccccc2)cc1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	4
Pfam Stratification	Homologous
Avg pChEMBL	7.35
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P14780	MMP9	Homo sapiens	Human	PF00040 PF00045 PF00413	8.3	IC50	ChEMBL;BindingDB
P08253	MMP2	Homo sapiens	Human	PF00040 PF00045 PF00413	8.0	IC50	ChEMBL;BindingDB
P50281	MMP14	Homo sapiens	Human	PF11857 PF00045 PF00413 PF01471	6.6	IC50	ChEMBL;BindingDB
P03956	MMP1	Homo sapiens	Human	PF00045 PF00413 PF01471	6.5	IC50	ChEMBL;BindingDB