JPENSYBRTSIYGO-CQSZACIVSA-N

InChIKey	`JPENSYBRTSIYGO-CQSZACIVSA-N`
Canonical SMILES	`COc1cc(-c2ccccc2)cc([C@H](C)C#Cc2c(C)nc(N)nc2N)c1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	7.47
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q27552	DHFR-TS	Cryptosporidium parvum	Pathogen	PF00186 PF00303	7.5	IC50	ChEMBL;BindingDB
P22906	DFR1	Candida albicans	Pathogen	PF00186	7.4	IC50	ChEMBL;BindingDB