Molecule Details
| InChIKey | JOJOWCOCCMULDU-UHFFFAOYSA-N |
|---|---|
| Compound Name | 6-Methoxy-3,4-dimethyl-1,8-dipyridin-3-ylimidazo[1,5-a]quinoxaline |
| Canonical SMILES | COc1cc(-c2cccnc2)cc2c1nc(C)c1c(C)nc(-c3cccnc3)n12 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.42 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q9Y233 | PDE10A | Homo sapiens | Human | PF01590 PF00233 | 10.0 | IC50 | ChEMBL;BindingDB |
| O00408 | PDE2A | Homo sapiens | Human | PF01590 PF00233 | 8.0 | IC50 | ChEMBL |
| O76074 | PDE5A | Homo sapiens | Human | PF01590 PF00233 | 6.6 | IC50 | ChEMBL |
| Q9HCR9 | PDE11A | Homo sapiens | Human | PF01590 PF00233 | 6.5 | IC50 | ChEMBL |
| P27815 | PDE4A | Homo sapiens | Human | PF18100 PF00233 | 6.0 | IC50 | ChEMBL |