Molecule Details
InChIKeyJNPRPMBJODOFEC-UHFFFAOYSA-N
Canonical SMILESCn1nccc1Nc1nccc(-c2cc3c(s2)C(C)(C)N(CCN2CCOCC2)C3=O)n1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL9.0
SourceChEMBL
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB18806
Drug NameTemuterkib
CAS Number1951483-29-6
Groups investigational
ATC Codes nan
Descriptionnan

Cross-references: CHEMBL4650285 ChemSpider: 60598689 PDB: KE8
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P28482 MAPK1 Homo sapiens Human PF00069 9.2 IC50 ChEMBL
P27361 MAPK3 Homo sapiens Human PF00069 8.8 IC50 ChEMBL
DrugBank Target Actions (1)
Target Gene Target Name Action Type
P28482 MAPK1 Mitogen-activated protein kinase 1 inhibitor targets