N-{6-cyano-1-[(1-methyl-1H-imidazol-5-yl)methyl]-1,2,3,4-tetrahydroquinolin-3-yl}-1-methyl-N-(2-methylprop-2-en-1-yl)-1H-imidazole-4-sulfonamide

InChIKey	`JNJBXYHGNTUTTK-UHFFFAOYSA-N`
Compound Name	N-{6-cyano-1-[(1-methyl-1H-imidazol-5-yl)methyl]-1,2,3,4-tetrahydroquinolin-3-yl}-1-methyl-N-(2-methylprop-2-en-1-yl)-1H-imidazole-4-sulfonamide
Canonical SMILES	`C=C(C)CN(C1Cc2cc(C#N)ccc2N(Cc2cncn2C)C1)S(=O)(=O)c1cn(C)cn1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	4
Pfam Stratification	Cross-Family
Avg pChEMBL	9.37
Source	BindingDB;ChEMBL;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P49354	FNTA	Homo sapiens	Human	PF01239	9.5	pIC50	TTD_MultiTarget
P49356	FNTB	Homo sapiens	Human	PF00432	9.5	IC50	ChEMBL
Q5E175	rhlE	Aliivibrio fischeri (strain ATCC 700601 / ES114)	Pathogen	PF00270 PF00271	9.2	IC50	BindingDB
Q5EI73		Plasmodium falciparum	Pathogen	PF01239	9.2	IC50	ChEMBL