3-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-[4-(4-methylpiperazin-1-yl)phenyl]-2H-pyrazolo[3,4-b]pyridine

InChIKey	`JNCFZEVZRYWROV-UHFFFAOYSA-N`
Compound Name	3-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-[4-(4-methylpiperazin-1-yl)phenyl]-2H-pyrazolo[3,4-b]pyridine
Canonical SMILES	`CN1CCN(c2ccc(-c3cnc4[nH]nc(-c5ccc6c(c5)OCCO6)c4c3)cc2)CC1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	7.48
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P06239	LCK	Homo sapiens	Human	PF07714 PF00017 PF00018	7.7	IC50	ChEMBL
Q8IVH8	MAP4K3	Homo sapiens	Human	PF00780 PF00069	7.7	IC50	ChEMBL
Q92918	MAP4K1	Homo sapiens	Human	PF00780 PF00069	7.1	IC50	ChEMBL