Molecule Details
InChIKeyJMIIFJIJWDCOEP-UHFFFAOYSA-N
Compound NameN-(2,5-dimethylphenyl)-2-(furan-2-yl)quinoline-4-carboxamide
Canonical SMILESCc1ccc(C)c(NC(=O)c2cc(-c3ccco3)nc3ccccc23)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)15
Pfam Stratification Cross-Family
Avg pChEMBL6.19
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (15)
Target Gene Organism Category Pfam pChEMBL Type Source
O14757 CHEK1 Homo sapiens Human PF00069 6.5 Ki ChEMBL
P53667 LIMK1 Homo sapiens Human PF00412 PF00595 PF07714 6.5 Ki ChEMBL
Q06418 TYRO3 Homo sapiens Human PF00041 PF07679 PF07714 6.5 Ki ChEMBL
P50750 CDK9 Homo sapiens Human PF00069 6.4 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.4 Ki ChEMBL
P08581 MET Homo sapiens Human PF07714 PF01437 PF01403 PF01833 6.2 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 6.2 Ki ChEMBL
P34947 GRK5 Homo sapiens Human PF00069 PF00615 6.1 Ki ChEMBL
O14965 AURKA Homo sapiens Human PF00069 6.0 Ki ChEMBL
P04629 NTRK1 Homo sapiens Human PF13855 PF16920 PF07714 PF18613 6.0 Ki ChEMBL
P29376 LTK Homo sapiens Human PF12810 PF07714 6.0 Ki ChEMBL
P49336 CDK8 Homo sapiens Human PF00069 6.0 Ki ChEMBL
P51817 PRKX Homo sapiens Human PF00069 6.0 Ki ChEMBL
Q00535 CDK5 Homo sapiens Human PF00069 6.0 Ki ChEMBL
Q9Y463 DYRK1B Homo sapiens Human PF00069 6.0 Ki ChEMBL