InChIKey	JKKFKPJIXZFSSB-CBZIJGRNSA-N
Canonical SMILES	C[C@]12CC[C@@H]3c4ccc(OS(=O)(=O)O)cc4CC[C@H]3[C@@H]1CCC2=O
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Cross-Family
Avg pChEMBL	6.84
Source	ChEMBL;BindingDB

DrugBank ID	DB04574
Drug Name	Estrone sulfate
CAS Number	481-97-0
Groups	approved
ATC Codes	nan
Description	Estrone sulfate (as estropipate) is a form of estrogen. It has several uses such as: alleviate symptoms of menopause as hormone replacement therapy, treatment some types of infertility, treatment of some conditions leading to underdevelopment of female sexual characteristics, treatment of vaginal at...

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Categories: 17-Ketosteroids Adrenal Cortex Hormones Contraceptive Agents, Hormonal Cytochrome P-450 CYP1A2 Inhibitors Cytochrome P-450 CYP1A2 Inhibitors (strength unknown) Cytochrome P-450 CYP1A2 Substrates Cytochrome P-450 CYP2C9 Inhibitors Cytochrome P-450 CYP2C9 Inhibitors (strength unknown) Cytochrome P-450 CYP2C9 Substrates Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 Enzyme Inhibitors Cytochrome P-450 Substrates Drugs that are Mainly Renally Excreted Estradiol Congeners Estranes Estrenes Estrogens Estrogens, Conjugated (USP) Fused-Ring Compounds Gonadal Hormones Gonadal Steroid Hormones Hormonal Contraceptives for Systemic Use Hormones Hormones, Hormone Substitutes, and Hormone Antagonists Hyperglycemia-Associated Agents Ketosteroids MATE 1 Substrates MATE 2 Substrates MATE substrates NTCP Inhibitors Reproductive Control Agents Steroids Thyroxine-binding globulin inducers

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Cross-references: BindingDB: 50366524 ChEBI: 17474 CHEMBL494753 ChemSpider: 2272513 Drugs Product Database (DPD): 4601 C02538 PharmGKB: PA165958342 PubChem:3001028 PubChem:46508976 Wikipedia: Estropipate ZINC: ZINC000003876186