Molecule Details
InChIKeyJKDGKIBAOAFRPJ-ZBINZKHDSA-N
Compound NameZimlovisertib
Canonical SMILESCC[C@@H]1[C@H](F)C(=O)N[C@@H]1COc1nccc2cc(C(N)=O)c(OC)cc12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Cross-Family
Avg pChEMBL7.8
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB15143
Drug NameZimlovisertib
CAS Number1817626-54-2
Groups investigational
ATC Codes nan
DescriptionPF-06650833 is under investigation in clinical trial NCT02609139 (Study to Evaluate Pharmacokinetics of A Modified Release Formulation of PF-06650833 in Healthy Subjects).

Categories: Amides Heterocyclic Compounds, Fused-Ring
Cross-references: BindingDB: 50239499 CHEMBL4081711 ChemSpider: 58805665 PDB: 8CG ZINC: ZINC000526061587
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9NWZ3 IRAK4 Homo sapiens Human PF07714 9.7 IC50 ChEMBL;BindingDB
P40337 VHL Homo sapiens Human PF01847 PF17211 7.5 IC50 ChEMBL
P78368 CSNK1G2 Homo sapiens Human PF12605 PF00069 6.2 IC50 ChEMBL