Molecule Details
| InChIKey | JKAOOUXUHVNVNM-UHFFFAOYSA-N |
|---|---|
| Compound Name | US10221163, Example 431 |
| Canonical SMILES | CCOC(=O)c1sc(N)nc1-c1cccc(-c2ccc(S(=O)(=O)NC(CN)CN)c(S(N)(=O)=O)c2-c2nnn[nH]2)c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 9.89 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| C7C422 | blaNDM-1 | Klebsiella pneumoniae | Pathogen | PF00753 | 10.1 | IC50 | ChEMBL;BindingDB |
| P52699 | Serratia marcescens | Pathogen | PF00753 | 9.9 | IC50 | BindingDB | |
| Q2QC95 | blaoxa-10 | Klebsiella pneumoniae | Pathogen | PF00905 | 9.8 | IC50 | BindingDB |
| Q5GN09 | vim-1 | Klebsiella pneumoniae | Pathogen | PF00753 | 9.8 | IC50 | BindingDB |