N-[7-[3-(1,3-dihydroisoindol-2-yl)propoxy]-6-methoxy-4-pyrrolidin-1-ylquinazolin-2-yl]-N',N'-dimethylethane-1,2-diamine

InChIKey	`JJRRWLVKNLMRSA-UHFFFAOYSA-N`
Compound Name	N-[7-[3-(1,3-dihydroisoindol-2-yl)propoxy]-6-methoxy-4-pyrrolidin-1-ylquinazolin-2-yl]-N',N'-dimethylethane-1,2-diamine
Canonical SMILES	`COc1cc2c(N3CCCC3)nc(NCCN(C)C)nc2cc1OCCCN1Cc2ccccc2C1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	6.5
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q9Y657	SPIN1	Homo sapiens	Human	PF02513	7.1	IC50	ChEMBL
Q9BPZ2	SPIN2B	Homo sapiens	Human	PF02513	6.2	Kd	ChEMBL
Q56A73	SPIN4	Homo sapiens	Human	PF02513	6.2	Kd	ChEMBL