Molecule Details
| InChIKey | JJKGYGMFHAYASJ-UHFFFAOYSA-N |
|---|---|
| Compound Name | N-[3-fluoro-4-[(6-methoxy-1,5-naphthyridin-4-yl)oxy]phenyl]-5-(4-fluoro-2-methylphenyl)-4-hydroxy-2-methylpyridine-3-carboxamide |
| Canonical SMILES | COc1ccc2nccc(Oc3ccc(NC(=O)c4c(C)ncc(-c5ccc(F)cc5C)c4O)cc3F)c2n1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.7 |
| Source | BindingDB |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P08581 | MET | Homo sapiens | Human | PF07714 PF01437 PF01403 PF01833 | 6.7 | IC50 | BindingDB |
| P35968 | KDR | Homo sapiens | Human | PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 | 6.7 | IC50 | BindingDB |
| Q12866 | MERTK | Homo sapiens | Human | PF00041 PF00047 PF13927 PF07714 | 6.7 | IC50 | BindingDB |