Molecule Details
InChIKeyJHYHWHUTTXJICB-UHFFFAOYSA-N
Compound Name7-Chloro-5-[[cyclohexyl(methyl)amino]methyl]quinolin-8-ol
Canonical SMILESCN(Cc1cc(Cl)c(O)c2ncccc12)C1CCCCC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)18
Pfam Stratification Cross-Family
Avg pChEMBL6.35
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (18)
Target Gene Organism Category Pfam pChEMBL Type Source
O14757 CHEK1 Homo sapiens Human PF00069 7.3 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 7.3 Ki ChEMBL
P53667 LIMK1 Homo sapiens Human PF00412 PF00595 PF07714 7.0 Ki ChEMBL
P08581 MET Homo sapiens Human PF07714 PF01437 PF01403 PF01833 6.7 Ki ChEMBL
P50750 CDK9 Homo sapiens Human PF00069 6.4 Ki ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 6.3 Ki ChEMBL
Q12851 MAP4K2 Homo sapiens Human PF00780 PF00069 6.3 Ki ChEMBL
Q9Y463 DYRK1B Homo sapiens Human PF00069 6.3 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 6.2 Ki ChEMBL
P07949 RET Homo sapiens Human PF00028 PF07714 PF17756 PF17812 PF17813 PF22540 6.1 Ki ChEMBL
P16234 PDGFRA Homo sapiens Human PF07679 PF25305 PF07714 6.1 Ki ChEMBL
P51955 NEK2 Homo sapiens Human PF00069 6.1 Ki ChEMBL
Q06418 TYRO3 Homo sapiens Human PF00041 PF07679 PF07714 6.1 Ki ChEMBL
Q8IU85 CAMK1D Homo sapiens Human PF00069 6.1 Ki ChEMBL
P04629 NTRK1 Homo sapiens Human PF13855 PF16920 PF07714 PF18613 6.0 Ki ChEMBL
P11309 PIM1 Homo sapiens Human PF00069 6.0 Ki ChEMBL
P29376 LTK Homo sapiens Human PF12810 PF07714 6.0 Ki ChEMBL
Q16288 NTRK3 Homo sapiens Human PF07679 PF00047 PF13855 PF16920 PF01462 PF07714 6.0 Ki ChEMBL