Molecule Details
InChIKeyJHVKBJJTUMIPIT-QQKFYDJZSA-N
Compound Name4-fluoro-N-[(8xi,9xi,14xi)-17-(4-methyl-1H-imidazol-1-yl)androsta-5,16-dien-3beta-yl]benzamide
Canonical SMILESCc1cn(C2=CCC3C4CC=C5C[C@@H](NC(=O)c6ccc(F)cc6)CC[C@]5(C)C4CC[C@]23C)cn1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)5
Pfam Stratification Cross-Family
Avg pChEMBL6.61
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (5)
Target Gene Organism Category Pfam pChEMBL Type Source
P05093 CYP17A1 Homo sapiens Human PF00067 7.0 IC50 ChEMBL
P03372 ESR1 Homo sapiens Human PF12743 PF00104 PF02159 PF00105 7.0 IC50 ChEMBL
P10275 AR Homo sapiens Human PF02166 PF00104 PF00105 6.7 IC50 ChEMBL
Q92731 ESR2 Homo sapiens Human PF12497 PF00104 PF00105 6.3 IC50 ChEMBL
P08684 CYP3A4 Homo sapiens Human PF00067 6.1 IC50 ChEMBL