Molecule Details
InChIKeyJFSGUSJACVSEKX-HAQNSBGRSA-N
Canonical SMILESCC(C)(C)c1cnc(CSc2cnc(N[C@H]3CC[C@H](N)CC3)s2)o1
Clinical Status Clinical Multi-Target
Targets (Human+Pathogen)7
Pfam Stratification Cross-Family
Avg pChEMBL7.03
SourceChEMBL;BindingDB;TTD_MultiTarget
2D Structure
2D structure
Activity Profile
Target Activities (7)
Target Gene Organism Category Pfam pChEMBL Type Source
P06493 CDK1 Homo sapiens Human PF00069 7.7 pIC50 TTD_MultiTarget
P24941 CDK2 Homo sapiens Human PF00069 7.7 pIC50 TTD_MultiTarget
O60563 CCNT1 Homo sapiens Human PF00134 PF21797 7.0 IC50 ChEMBL
P50613 CDK7 Homo sapiens Human PF00069 7.0 IC50 ChEMBL;BindingDB
P51946 CCNH Homo sapiens Human PF16899 PF00134 7.0 IC50 ChEMBL
P50750 CDK9 Homo sapiens Human PF00069 6.7 IC50 ChEMBL;BindingDB
P14635 CCNB1 Homo sapiens Human PF02984 PF00134 6.1 IC50 ChEMBL