[C(E)]-4-Amino-6-[[1-[(3-fluorophenyl)methyl]-1H-indazol-5-yl]amino]-5-pyrimidinecarboxaldehyde oxime

InChIKey	`JFOADMWQXWRMGB-YCPBAFNGSA-N`
Compound Name	[C(E)]-4-Amino-6-[[1-[(3-fluorophenyl)methyl]-1H-indazol-5-yl]amino]-5-pyrimidinecarboxaldehyde oxime
Canonical SMILES	`Nc1ncnc(Nc2ccc3c(cnn3Cc3cccc(F)c3)c2)c1/C=N/O`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	7.92
Source	ChEMBL;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P00533	EGFR	Homo sapiens	Human	PF00757 PF14843 PF07714 PF01030 PF21314	7.9	IC50	ChEMBL
P04626	ERBB2	Homo sapiens	Human	PF00757 PF14843 PF07714 PF01030 PF21314	7.9	pIC50	TTD_MultiTarget