[4-(5-Chloro-3-isopropyl-1H-pyrazol-4-yl)-pyrimidin-2-yl]-[5-(3,3-dimethyl-piperazin-1-yl)-pyridin-2-yl]-amine

InChIKey	`JEEUJOMJWBHMCS-UHFFFAOYSA-N`
Compound Name	[4-(5-Chloro-3-isopropyl-1H-pyrazol-4-yl)-pyrimidin-2-yl]-[5-(3,3-dimethyl-piperazin-1-yl)-pyridin-2-yl]-amine
Canonical SMILES	`CC(C)c1n[nH]c(Cl)c1-c1ccnc(Nc2ccc(N3CCNC(C)(C)C3)cn2)n1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	7.8
Source	ChEMBL;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P11802	CDK4	Homo sapiens	Human	PF00069	7.8	pIC50	TTD_MultiTarget
P24385	CCND1	Homo sapiens	Human	PF02984 PF00134	7.8	IC50	ChEMBL
P24941	CDK2	Homo sapiens	Human	PF00069	7.8	pIC50	TTD_MultiTarget