N-[3,5-Difluoro-4-(Trifluoromethyl)phenyl]-5-Methyl-2-(Trifluoromethyl)[1,2,4]triazolo[1,5-A]pyrimidin-7-Amine

InChIKey	`JEEOGRYTTNEULC-UHFFFAOYSA-N`
Compound Name	N-[3,5-Difluoro-4-(Trifluoromethyl)phenyl]-5-Methyl-2-(Trifluoromethyl)[1,2,4]triazolo[1,5-A]pyrimidin-7-Amine
Canonical SMILES	`Cc1cc(Nc2cc(F)c(C(F)(F)F)c(F)c2)n2nc(C(F)(F)F)nc2n1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	7.75
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q54A96	dhod	Plasmodium falciparum	Pathogen	PF01180	7.8	IC50	ChEMBL
Q08210		Plasmodium falciparum (isolate 3D7)	Pathogen	PF01180	7.7	IC50	ChEMBL;BindingDB