Molecule Details
InChIKeyJDRSQGJWTVRNGM-QFBILLFUSA-N
Compound NameN-((3S,4S)-4-((6-Amino-4-methylpyridin-2-YL)methyl)pyrrolidin-3-YL)-N'-(4-chlorobenzyl)ethane-1,2-diamine
Canonical SMILESCc1cc(N)nc(C[C@H]2CNC[C@H]2NCCNCc2ccc(Cl)cc2)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL7.82
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB08018
Drug NameN-{(3S,4S)-4-[(6-AMINO-4-METHYLPYRIDIN-2-YL)METHYL]PYRROLIDIN-3-YL}-N'-(4-CHLOROBENZYL)ETHANE-1,2-DIAMINE
CAS Numbernan
Groups experimental
ATC Codes nan
Descriptionnan

Cross-references: BindingDB: 29234 CHEMBL474637 ChemSpider: 24697467 PDB: JI3 PubChem:24798097 PubChem:99444489 ZINC: ZINC000039036155
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P29475 NOS1 Homo sapiens Human PF00667 PF00258 PF00175 PF02898 PF00595 8.6 Ki ChEMBL;BindingDB
P29474 NOS3 Homo sapiens Human PF00667 PF00258 PF00175 PF02898 7.1 Ki ChEMBL
DrugBank Target Actions (2)
Target Gene Target Name Action Type
P29474 NOS3 Nitric oxide synthase 3 binder targets
P29475 NOS1 Nitric oxide synthase 1 binder targets