Molecule Details
| InChIKey | JDARDSVOVYVQST-MRXNPFEDSA-N |
|---|---|
| Compound Name | Fulacimstat |
| Canonical SMILES | Cn1c(=O)oc2cc(-n3cc(C(=O)O)c(=O)n([C@@H]4CCc5c4cccc5C(F)(F)F)c3=O)ccc21 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.62 |
| Source | BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB15085 |
|---|---|
| Drug Name | Fulacimstat |
| CAS Number | 1488354-15-9 |
| Groups | investigational |
| ATC Codes | nan |
| Description | Fulacimstat is under investigation in clinical trial NCT02452515 (A Single-blind Pilot Study to Investigate Safety and Tolerability of the Chymase Inhibitor BAY1142524 in Clinically Stable Patients With Left-ventricular Dysfunction). |
Categories: Enzyme Inhibitors
Cross-references: BindingDB: 256011 ChemSpider: 64835239