Molecule Details
InChIKeyJCXULQAGBNATOH-UHFFFAOYSA-N
Compound NamePyrazoloquinazoline deriv., 27
Canonical SMILESCCCN(CCO)CCCOc1cc2ncnc(Nc3cc(CC(=O)Nc4cccc(F)c4)[nH]n3)c2cc1OC
Clinical Status Clinical Multi-Target
Targets (Human+Pathogen)3
Pfam Stratification Homologous
Avg pChEMBL7.34
SourceChEMBL;BindingDB;TTD_MultiTarget
2D Structure
2D structure
Activity Profile
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
Q96GD4 AURKB Homo sapiens Human PF00069 8.7 IC50 ChEMBL;BindingDB
O14965 AURKA Homo sapiens Human PF00069 6.7 IC50 ChEMBL;BindingDB
O75716 STK16 Homo sapiens Human PF00069 6.7 pIC50 TTD_MultiTarget