Molecule Details
| InChIKey | JBGQCEANEMDCFH-UHFFFAOYSA-N |
|---|---|
| Compound Name | ethyl 6-(4-chlorophenyl)-4-(4-sulfamoylphenyl)-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylate |
| Canonical SMILES | CCOC(=O)C1=C(c2ccc(Cl)cc2)NC(=S)NC1c1ccc(S(N)(=O)=O)cc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.24 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P43166 | CA7 | Homo sapiens | Human | PF00194 | 7.8 | Ki | ChEMBL |
| P00918 | CA2 | Homo sapiens | Human | PF00194 | 7.6 | Ki | ChEMBL |
| O43570 | CA12 | Homo sapiens | Human | PF00194 | 7.5 | Ki | ChEMBL |
| Q16790 | CA9 | Homo sapiens | Human | PF00194 | 7.2 | Ki | ChEMBL |
| P00915 | CA1 | Homo sapiens | Human | PF00194 | 6.1 | Ki | ChEMBL |