JAWPAUHQCGKVGI-GFCCVEGCSA-N

InChIKey	`JAWPAUHQCGKVGI-GFCCVEGCSA-N`
Canonical SMILES	`COc1cccc([C@@H](C)NC(=O)c2cc3ccc(-c4cn[nH]c4)nc3[nH]2)c1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	8.61
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
O75116	ROCK2	Homo sapiens	Human	PF25346 PF00069 PF08912	9.0	IC50	ChEMBL;BindingDB
Q13464	ROCK1	Homo sapiens	Human	PF25346 PF00069 PF08912	8.2	IC50	ChEMBL;BindingDB