Molecule Details
| InChIKey | IZYHVTAYLHFZSP-UHFFFAOYSA-N |
|---|---|
| Compound Name | Antibacterial agent 27 |
| Canonical SMILES | N#Cc1ccc(Cn2ccc3c4c(N)nc(N)nc4ccc32)cc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.98 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P00374 | DHFR | Homo sapiens | Human | PF00186 | 8.2 | IC50 | ChEMBL;BindingDB |
| P11166 | SLC2A1 | Homo sapiens | Human | PF00083 | 6.1 | IC50 | ChEMBL |
| P00381 | folA | Lacticaseibacillus casei | Pathogen | PF00186 | 8.2 | IC50 | ChEMBL;BindingDB |
| O61059 | LmGT2 | Leishmania mexicana | Pathogen | PF00083 | 6.3 | IC50 | ChEMBL |
| O97467 | ht1 | Plasmodium falciparum | Pathogen | PF00083 | 6.2 | IC50 | ChEMBL |