Molecule Details
| InChIKey | IZVPWZQAMQFEGX-UHFFFAOYSA-N |
|---|---|
| Compound Name | 2,3,5,6-Tetrafluoro-4-(4lambda4-thia-2,3,7-triazatricyclo[6.4.0.02,6]dodeca-1(12),3,4,6,8,10-hexaen-5-ylsulfanyl)benzenesulfonamide |
| Canonical SMILES | NS(=O)(=O)c1c(F)c(F)c(SC2=S=Nn3c2nc2ccccc23)c(F)c1F |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.2 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P00915 | CA1 | Homo sapiens | Human | PF00194 | 9.4 | Kd | ChEMBL;BindingDB |
| Q8N1Q1 | CA13 | Homo sapiens | Human | PF00194 | 8.6 | Kd | ChEMBL;BindingDB |
| P00918 | CA2 | Homo sapiens | Human | PF00194 | 8.2 | Kd | ChEMBL;BindingDB |
| P43166 | CA7 | Homo sapiens | Human | PF00194 | 7.9 | Kd | ChEMBL;BindingDB |
| O43570 | CA12 | Homo sapiens | Human | PF00194 | 7.0 | Kd | ChEMBL;BindingDB |