N-benzyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)benzamide

InChIKey	`IZAVTOABECKIDH-UHFFFAOYSA-N`
Compound Name	N-benzyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)benzamide
Canonical SMILES	`O=C(NCc1ccccc1)c1cccc(-c2cnc3[nH]ccc3c2)c1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	20
Pfam Stratification	Cross-Family
Avg pChEMBL	6.6
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q9UEE5	STK17A	Homo sapiens	Human	PF00069	7.8	Ki	ChEMBL
Q12851	MAP4K2	Homo sapiens	Human	PF00780 PF00069	7.6	Ki	ChEMBL
O95819	MAP4K4	Homo sapiens	Human	PF00780 PF00069	7.0	Ki	ChEMBL
P16591	FER	Homo sapiens	Human	PF00611 PF07714 PF00017	6.9	Ki	ChEMBL
O96017	CHEK2	Homo sapiens	Human	PF00498 PF00069	6.8	Ki	ChEMBL
P17948	FLT1	Homo sapiens	Human	PF07679 PF00047 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854	6.8	Ki	ChEMBL
Q96GD4	AURKB	Homo sapiens	Human	PF00069	6.8	Ki	ChEMBL
Q9HBH9	MKNK2	Homo sapiens	Human	PF00069	6.8	Ki	ChEMBL
P36888	FLT3	Homo sapiens	Human	PF00047 PF07714	6.7	Ki	ChEMBL
P07332	FES	Homo sapiens	Human	PF00611 PF07714 PF00017	6.6	Ki	ChEMBL
Q8NE63	HIPK4	Homo sapiens	Human	PF00069	6.6	Ki	ChEMBL
Q16288	NTRK3	Homo sapiens	Human	PF07679 PF00047 PF13855 PF16920 PF01462 PF07714	6.5	Ki	ChEMBL
O60674	JAK2	Homo sapiens	Human	PF18379 PF18377 PF17887 PF07714 PF21990	6.3	Ki	ChEMBL
Q15303	ERBB4	Homo sapiens	Human	PF00757 PF14843 PF07714 PF01030 PF21314	6.2	Ki	ChEMBL
Q9Y4K4	MAP4K5	Homo sapiens	Human	PF00780 PF00069	6.2	Ki	ChEMBL
P08922	ROS1	Homo sapiens	Human	PF00041 PF07714	6.1	Ki	ChEMBL
Q13464	ROCK1	Homo sapiens	Human	PF25346 PF00069 PF08912	6.1	Ki	ChEMBL
Q7KZI7	MARK2	Homo sapiens	Human	PF02149 PF00069 PF00627	6.1	Ki	ChEMBL
Q8N4C8	MINK1	Homo sapiens	Human	PF00780 PF00069	6.1	Ki	ChEMBL
P35968	KDR	Homo sapiens	Human	PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854	6.0	Ki	ChEMBL