Molecule Details
| InChIKey | IYJZRZIDVYDIHE-UHFFFAOYSA-N |
|---|---|
| Compound Name | 6-(ethylcarbamoylamino)-4-(4-hydroxyanilino)-N-pyridin-3-ylpyridine-3-carboxamide |
| Canonical SMILES | CCNC(=O)Nc1cc(Nc2ccc(O)cc2)c(C(=O)Nc2cccnc2)cn1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.41 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P0A0K8 | gyrB | Staphylococcus aureus | Pathogen | PF00204 PF00986 PF02518 PF01751 | 7.6 | IC50 | ChEMBL;BindingDB |
| P0AES4 | gyrA | Escherichia coli (strain K12) | Pathogen | PF03989 PF00521 | 7.5 | IC50 | ChEMBL |
| P0C1S7 | parE | Staphylococcus aureus | Pathogen | PF00204 PF00986 PF02518 PF01751 | 7.1 | IC50 | ChEMBL |