1-(5',11'-Dihydrospiro[cyclopentane-1,10'-dibenzo[a,d]cyclohepten]-3-yl)-4-hydroxy-4-piperidinecarboxylic acid

InChIKey	`IYAJUPFWKMPDJJ-UHFFFAOYSA-N`
Compound Name	1-(5',11'-Dihydrospiro[cyclopentane-1,10'-dibenzo[a,d]cyclohepten]-3-yl)-4-hydroxy-4-piperidinecarboxylic acid
Canonical SMILES	`O=C(O)C1(O)CCN(C2CCC3(Cc4ccccc4Cc4ccccc43)C2)CC1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	4
Pfam Stratification	Homologous
Avg pChEMBL	6.95
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P35367	HRH1	Homo sapiens	Human	PF00001	7.3	Ki	ChEMBL;BindingDB
P28223	HTR2A	Homo sapiens	Human	PF00001	7.0	Ki	ChEMBL
P28335	HTR2C	Homo sapiens	Human	PF00001	6.9	Ki	ChEMBL
P41595	HTR2B	Homo sapiens	Human	PF00001	6.6	Ki	ChEMBL