Molecule Details
| InChIKey | IXZOHGPZAQLIBH-UHFFFAOYSA-N |
|---|---|
| Compound Name | 3-(4-((4-(Morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione |
| Canonical SMILES | O=C1CCC(N2Cc3c(OCc4ccc(CN5CCOCC5)cc4)cccc3C2=O)C(=O)N1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 6 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 8.19 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (6)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P01584 | IL1B | Homo sapiens | Human | PF00340 PF02394 | 9.1 | IC50 | ChEMBL;BindingDB |
| P01375 | TNF | Homo sapiens | Human | PF00229 | 8.7 | IC50 | ChEMBL;BindingDB |
| Q14676 | MDC1 | Homo sapiens | Human | PF16589 PF00498 PF16770 | 8.6 | IC50 | BindingDB |
| P04141 | CSF2 | Homo sapiens | Human | PF01109 | 8.0 | IC50 | BindingDB |
| P05231 | IL6 | Homo sapiens | Human | PF00489 | 8.0 | IC50 | BindingDB |
| P10147 | CCL3 | Homo sapiens | Human | PF00048 | 6.7 | IC50 | BindingDB |