InChIKey	IXXFZUPTQVDPPK-ZAWHAJPISA-N
Compound Name	Solithromycin
Canonical SMILES	CC[C@H]1OC(=O)[C@@](C)(F)C(=O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@](C)(OC)C[C@@H](C)C(=O)[C@H](C)[C@H]2N(CCCCn3cc(-c4cccc(N)c4)nn3)C(=O)O[C@]12C
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	55
Pfam Stratification	Cross-Family
Avg pChEMBL	8.22
Source	ChEMBL

DrugBank ID	DB09308
Drug Name	Solithromycin
CAS Number	760981-83-7
Groups	investigational
ATC Codes	J01FA16
Description	Solithromycin is a ketolide antibiotic undergoing clinical development for the treatment of community-acquired pneumonia (CAP) and other infections.

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Categories: Anti-Bacterial Agents Anti-Infective Agents Antibacterials for Systemic Use Antiinfectives for Systemic Use Cytochrome P-450 CYP3A Inhibitors Cytochrome P-450 CYP3A4 Inhibitors Cytochrome P-450 CYP3A4 Inhibitors (strength unknown) Cytochrome P-450 Enzyme Inhibitors Ketolides Lactones Macrolides Macrolides, Lincosamides and Streptogramins Polyketides

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Cross-references: CHEMBL1232510 ChemSpider: 25056854 PDB: EM1 PubChem:25242512 PubChem:310265196 Wikipedia: Solithromycin ZINC: ZINC000095627834