Molecule Details
| InChIKey | IXRCZLGBPPMVSP-UHFFFAOYSA-N |
|---|---|
| Compound Name | 3-methyl-5-[5-methyl-4-[[4-(trifluoromethyl)phenyl]methyl]-1,2,4-triazol-3-yl]-2H-indazole |
| Canonical SMILES | Cc1n[nH]c2ccc(-c3nnc(C)n3Cc3ccc(C(F)(F)F)cc3)cc12 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 9 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.47 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (9)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P24863 | CCNC | Homo sapiens | Human | PF16899 PF00134 | 9.2 | IC50 | ChEMBL |
| P49336 | CDK8 | Homo sapiens | Human | PF00069 | 9.2 | IC50 | ChEMBL |
| Q9BWU1 | CDK19 | Homo sapiens | Human | PF00069 | 8.7 | IC50 | ChEMBL |
| P49760 | CLK2 | Homo sapiens | Human | PF00069 | 7.2 | Kd | ChEMBL |
| P49759 | CLK1 | Homo sapiens | Human | PF00069 | 7.0 | Kd | ChEMBL |
| P49841 | GSK3B | Homo sapiens | Human | PF00069 | 6.7 | Kd | ChEMBL |
| P49840 | GSK3A | Homo sapiens | Human | PF00069 | 6.6 | Kd | ChEMBL |
| Q9NRM7 | LATS2 | Homo sapiens | Human | PF00069 PF00433 | 6.6 | Kd | ChEMBL |
| Q9Y6M4 | CSNK1G3 | Homo sapiens | Human | PF12605 PF00069 | 6.1 | Kd | ChEMBL |