Molecule Details
InChIKeyIWODHENDABKBRB-OYSWKTHDSA-N
Compound Name[(2S,3R,4R,5R)-5-[4-amino-3-(4-methylphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-3-methyl-4-prop-2-ynoxyoxolan-2-yl]methyl ethenesulfonate
Canonical SMILESC#CCO[C@@H]1[C@H](C)[C@@H](COS(=O)(=O)C=C)O[C@H]1n1nc(-c2ccc(C)cc2)c2c(N)ncnc21
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)6
Pfam Stratification Homologous
Avg pChEMBL7.66
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (6)
Target Gene Organism Category Pfam pChEMBL Type Source
P07947 YES1 Homo sapiens Human PF07714 PF00017 PF00018 8.6 IC50 ChEMBL
P12931 SRC Homo sapiens Human PF07714 PF00017 PF00018 8.2 IC50 ChEMBL
P07948 LYN Homo sapiens Human PF07714 PF00017 PF00018 8.1 IC50 ChEMBL
P00519 ABL1 Homo sapiens Human PF08919 PF07714 PF00017 PF00018 7.5 IC50 ChEMBL
P35968 KDR Homo sapiens Human PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 7.1 IC50 ChEMBL
P22607 FGFR3 Homo sapiens Human PF21165 PF07679 PF13927 PF07714 6.6 IC50 ChEMBL